Double embryo transfer of a euploid blastocyst after a failed single embryo transfer does not improve live birth rate but significantly increases the risk of twins

Double embryo transfer of a euploid blastocyst after a failed single embryo transfer does not improve live birth rate but significantly increases the risk of twins
Improvements in extended culture, trophectoderm biopsy, 24 chromosome preimplantation genetic screening (PGS), and vitrification protocols have significantly increased the utilization of elective single embryo transfer1. This new paradigm has significantly improved the safety of assisted reproductive technologies by reducing the incidence of multiple gestations after treatment2. However, a euploid SET still fails in approximately 1/3 of good prognosis patients. Thus, patients and clinicians are often faced with a decision of whether or not to try another single embryo transfer or to increase transfer order in an attempt to improve the likelihood of delivery.
Source: fertstert.org