Growth disparities in uterine leiomyomas associated with MED12 mutation

Growth disparities in uterine leiomyomas associated with MED12 mutation
Uterine leiomyoma is the most common benign estrogen (E)-dependent tumor in women of reproductive age. Approximately 25% of women are affected and the cumulative incidence is 70% of women by the age of 50 years. In addition, this tumor is more prevalent at younger ages, and is more common in African-American women (73%) compared to White women (45%). Uterine leiomyoma comprises smooth muscle cells derived from the myometrium and an extracellular matrix rich in collagen, fibronectin, and proteoglycans.
Source: fertstert.org