To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context?

To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context?
First do no harm—how can this key medical concept be interpreted in the reproductive medicine of the 21st century where scientific developments allow us to prevent the birth of a child with a genetic condition?
Source: fertstert.org